If the increase is only mild, you can continue to take the drug.

Occasionally, statin use could cause an increase in the level of enzymes that signal liver inflammation. Rhabdomyolysis can occur when you take statins in combination with certain drugs or if you take a high dose of statins. The risk of very serious side effects is extremely low, and calculated in a few cases per million people taking statins. Rhabdomyolysis can cause severe muscle pain, liver damage, kidney failure and death. Very rarely, statins can cause life-threatening muscle damage called rhabdomyolysis (rab-doe-my-OL-ih-sis). However, studies have found that nearly 30 percent of people stopped taking the pills because of muscle aches even when they were taking a placebo.Ī strong predictor you'll experience muscle aches when taking statins could be whether or not you read about the potential side effect. The actual risk of developing muscle pain as a result of taking statins is about 5 percent or less compared with taking a pill that doesn't contain medication (placebo). A 'nocebo' effect means people who have negative expectations about a medication report experiencing the potential side effect at higher rates than the drug should cause. However, researchers have found a 'nocebo' effect when it comes to perceived muscle pain and statins.

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